Welcome!
Notice: New FY25 fee rates will be implemented for service requests received after July 1, 2024. After more than 10 years of generous SKCC subsidies and no fee increases, new rates sanctioned by SKCC Shared Resources leadership in 2023 are now being implemented. The TPSR strives for high-quality services that remain highly subsidized by SKCC and are below the rates offered at comparable institutions.
Notice: Longer turn-around times: Our long-time manager, Dr. Zhijiu Zhong, has left TJU/SKCC after 17 years of outstanding service for an opportunity in industry. We are working to recruit a new manager. The core is currently understaffed, so please be understanding with the personnel. Our turn-around times are longer than usual, and we are working to remedy this.
TPSR Sample Drop-Off and Pick-Up procedures:
We strongly suggest that our users set up a consultation meeting if you are our first-time client or before harvesting/sampling for a new project. We will review and discuss the sample collection and preparation procedures/protocols to ensure the best outcome for your precious samples, which will both properly illustrate the desired features of the anatomical and histopathological details and be compatible with your scientific research object as well as future analysis. This initial remote or in-person consultation is free of charge to our clients.
For routine requests, such as fixed tissue samples for paraffin processing, embedding, sectioning, H&E stain and Special Stain; paraffin blocks for sectioning and staining; paraffin slides for staining; whole slides scanning, etc., walk-in drop-off/pick-up are welcome during our work hours (Mon-Fri, 8:15 am to 4:45 pm).
For Equipment Reservations, Training/Consultation Requests, Frozen Requests as well as IHC/ISH Requests, please contact the Shared Resource (Tel: 215-503-3858/215-503-8826 or Email hallgeir.rui@jefferson.edu) to schedule an appointment with this shared resource.
When dropping off:
NEVER-EVER drop off samples without communicating with our staff. Leaving materials unnotified might jeopardize the research request/project.
Important Information about Aperio CS2 ScanScope Brightfield Slide Scanning Service
Below are requirements and suggestions for you to utilize this service:
In “Describe what you need” area, tell Jeff IS&T that you need uninstall old version ImageScope software in your PC (Include the PCS# of on the Jeff IS&T service tag attached to the PC) and install the latest version (version 12.4.6.5003) of ImageScope software. Mention that the software was downloaded and saved on desktop.
About us:
The Translational Pathology Shared Resource provides a full range, state-of-the-art, detail-orientated, outstanding array of experimental histopathology services complemented by molecular pathology, digital pathology, and veterinary hematology services to SKCC members, TJU, and the local research community in the greater Philadelphia area. In collaboration with our internal labs at TJU, we also facilitate the interactions between investigators and SKCC Biorepository and Pathology Department to access human tissue samples and perform Laser Capture Microdissection of tissues to capture individual cells. Over one hundred principal investigators use the Translational Pathology Shared Resource, and the core has provided key data that support many publications and grant applications.
The mission of this shared resource is to provide:
Full range outstanding array of experimental histopathology services, including paraffin and frozen tissue processing, slide preparation, histochemical staining (H&E and Special Stains)
Immunohistochemistry (IHC) staining is performed on paraffin sections, frozen tissue, or cytological preparations and utilizes a broad range of optimized commercial antibodies or antibodies provided by the investigator with an automatic staining platform: DAKO Autostainer Plus and Biocare Medical IntelliPATH FLX®.
TUNEL Labelling and in situ Hybridization using RNAscope® technique
Light field whole slides scanning (20X and 40X) with Aperio CS2 ScanScope. Link to our Image server: SKCC TPSR eSlideManager Server Link
For all first-time users, please watch iLab user tutorials videos.
The procedures are:
1. PI and lab members planning to use SKCC shared resources under iLab must register in the iLab system.
2. Internal users will use their Jefferson campus credentials to log in after registering in the system.
3. External users can generate their username and password. The PI should register first so that their lab members can register under the PI’s lab.
4. Both internal and external PIs need to review and accept/approve the lab member’s membership request in the iLab system before the lab member can join and utilize the iLab portal.
See instruction: How to manage membership request and charge codes (for PI)
See iLab registration link: https://skcc-pa.ilabsolutions.com/landing/2792
5. For internal users, PI needs to set up payment information with our IT expert Ryan Smalley (Tel: 3-9692, Email: Ryan.Smalley@jefferson.edu) after the registration.
6. For external users, please generate a PO (Purchase Order) before submitting the request to us.
No request will go through the iLab system to us without payment information.
7. For internal users, PI needs to assign a charge code to their lab members to allow them to access the charge code. See instructions How to manage membership request and charge codes (for PI)
8. After PI assigns the charge code, the lab member can submit a request to us in the iLab portal under Request Service tab.
a. When filling out the 'Describe Work Requested in FULL DETAIL', please include at a minimum the following information, and consider adding other key relevant information:
b. Enter the sample "label” in the request form:
c. Enter the Charge Code or Purchase Order under payment information.
d. Check all information entered above to make sure it is correct.
e. Click the Submit button to submit the request to this shared resource if you are ready to do so. Otherwise, click "save draft of form" at the end of "Forms and Request Details" to save it under your account.
f. Use the printer icon"
" under "Forms and Request Details" to download a PDF file and print it out.
g. Please submit the request sheet together with the samples to us.
9. For Equipment Reservation, Training/Consultation Request, CBC Analysis request, Frozen Request as well as IHC/ISH Request, please always call 215-503-3858/8826 or email us to schedule an appointment before submitting the samples/request to this shared resource.
10. No appointment is needed to submit samples for routine paraffin processing or blocks.
11. We will review, update, and confirm the request details with users and process the request once we receive the hard copy of the request sheet and all related materials.
12. Once we complete the request and update the request status to "completed," an automatic email (from no-reply@ilabsolutions.com titled "NOTIFICATION: XXXX The Service request TR/PSR-XX-XXXX has been completed") will be sent to you. This means you can come and pick up your completed work during our work hours; no appointment is needed unless there are temperature—and/or time-sensitive materials involved.
Hallgeir Rui, MD, PhD | Director
Haifeng Yang, PhD | Co-Director
Position Posted | Laboratory Manager
| Hours:
8:30 AM - 4:30 PM Monday - Friday except Holidays |
Address: 233 S. 10th Street |
|
Telephone: 215-503-3858/8826/2237 |
|
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Hallgeir Rui, MD, PhD |
Director
|
(215) 503-9881
|
hallgeir.rui@jefferson.edu
|
Bluemle Life Sciences Building, Rm 1008
|
| Haifeng Yang, PhD |
Co-Director
|
(215) 503-6163
|
haifeng.yang@jefferson.edu
|
Jefferson Alumni Hall, 336D
|
| Position posted |
Laboratory Manager
|
Bluemle Life Sciences Building, Rm 815
|
||
| Natalie Dougherty, MS |
Research Assistant III
|
(215) 503-3858/8826/2237
|
natalie.dougherty@jefferson.edu
|
Bluemle Life Sciences Building, Rm 815
|
| Ruiyan Jing, BA |
Research Assistant I
|
(215) 503-3858/8826/2237
|
ruiyan.jing@jefferson.edu
|
Bluemle Life Sciences Building, Rm 815
|
Research Assistant I
|
